N-Methyl-3-piperidyl benzilate

Source: Wikipedia, the free encyclopedia.
N-Methyl-3-piperidyl benzilate
Legal status
Legal status
Identifiers
  • (1-Methylpiperidin-3-yl) 2-hydroxy-2,2-di(phenyl)acetate
JSmol)
  • O=C(OC1CCCN(C)C1)C(O)(c2ccccc2)c3ccccc3
  • InChI=1S/C20H23NO3/c1-21-14-8-13-18(15-21)24-19(22)20(23,16-9-4-2-5-10-16)17-11-6-3-7-12-17/h2-7,9-12,18,23H,8,13-15H2,1H3 checkY
  • Key:ZBEILXWHVSVDBN-UHFFFAOYSA-N checkY
  (verify)

N-Methyl-3-piperidyl benzilate (JB-336 or LBJ) is an

3-quinuclidinyl benzilate
.

N-methyl-3-piperidyl benzilate is less potent and shorter acting than 3-quinuclidyl benzilate, but like 3-QNB its effects on the central nervous system predominate over peripheral effects. It produces

dry mouth tend to make abuse of drugs of this kind uncommon. Both the N-methyl and N-ethyl analogues of 3-piperidyl benzilate are, however, Schedule I
controlled drugs.

muscarinic acetylcholine receptors in the brain.[1]

Methylation of JB-336 gives the

Mepenzolate bromide
.

See also

References

  1. PMID 10070712
    .
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