NBOMe-mescaline

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NBOMe-mescaline
intravenous
ATC code
  • none
Legal status
Legal status
  • DE: NpSG (Industrial and scientific use only)
  • UK: Class A
  • US: Unscheduled
Pharmacokinetic data
Elimination half-life?
Identifiers
  • N-(2-Methoxybenzyl)-2-(3,4,5-trimethoxyphenyl)ethan-1-amine
JSmol)
  • COC1=CC(CCNCC2=C(OC)C=CC=C2)=CC(OC)=C1OC.Cl
  • InChI=1S/C19H25NO4/c1-21-16-8-6-5-7-15(16)13-20-10-9-14-11-17(22-2)19(24-4)18(12-14)23-3/h5-8,11-12,20H,9-10,13H2,1-4H3 checkY
  • Key:USPSMWCGHVXKMN-UHFFFAOYSA-N checkY

NBOMe-mescaline or mescaline-NBOMe is a synthetic substituted phenethylamine. It is a partial agonist of serotonin receptors with a 5-HT2A pKi originally reported as 7.3 (i.e. Ki of approximately 50nM),[1] though more modern techniques assayed it as 140nM at 5-HT2A and 640nM at 5-HT2C, making it one of the least potent compounds among the N-benzyl phenethylamines.[2]

History

NBOMe-mescaline and

NBOMes
became available.

Properties and chemistry

Solubility of the

DMSO.[4]

Synthesis

NBOMe-mescaline can be synthesized from

Lithium Aluminium Hydride
as a reducing agent.

Psychedelic dosage in humans

There have been very few reports of human use of NBOMe-mescaline. Psychedelic visual, auditory and mental effects start around 50 mg intranasally.[5]

Legal status

NBOMe-mescaline is not listed in the schedules set out by the United Nations' Single Convention on Narcotic Drugs from 1961 nor their Convention on Psychotropic Substances from 1971,[6] so the signatory countries to these international drug control treaties are not required by said treaties to control NBOMe-mescaline.

United States

NBOMe-mescaline is not listed in the

possession could potentially be prosecuted under the Federal Analogue Act.[8]

United Kingdom

This substance is a

Class A drug in the United Kingdom as a result of the N-benzylphenethylamine catch-all clause in the Misuse of Drugs Act 1971.[9]

See also

References

  1. ^ a b Pertz HH, Rheineck A, Elz S (1999). "N-Benzylated derivatives of the hallucinogenic drugs mescaline and escaline as partial agonists at rat vascular 5-HT2A receptors". Naunyn-Schmiedeberg's Arch Pharmacol. 359 (Suppl 3): R29. Archived from the original on September 25, 2015.
  2. S2CID 10382311
    .
  3. ^ 25B-NB (n-Benzyl-2C-B) @ BlueLight.org
  4. ^ Cayman Chemical's Mescaline NBOMe HCl MSDS
  5. ^ The Big & Dandy NBOMe-Mescaline Thread @ BlueLight.org
  6. ^ UN International Drug Control Conventions
  7. ^ §1308.11 Schedule I.
  8. ^ Erowid Analog Law Vault : Federal Controlled Substance Analogue Act Summary
  9. ^ "The Misuse of Drugs Act 1971 (Ketamine etc.) (Amendment) Order 2014". UK Statutory Instruments 2014 No. 1106. www.legislation.gov.uk.

External links

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