Niravoline

Add links
Source: Wikipedia, the free encyclopedia.
Niravoline
Names
Preferred IUPAC name
N-Methyl-2-(3-nitrophenyl)-N-[(1S,2S)-2-(pyrrolidin-1-yl)-2,3-dihydro-1H-inden-1-yl]acetamide
Identifiers
3D model (
JSmol
)
UNII
  • InChI=1S/C22H25N3O3/c1-23(21(26)14-16-7-6-9-18(13-16)25(27)28)22-19-10-3-2-8-17(19)15-20(22)24-11-4-5-12-24/h2-3,6-10,13,20,22H,4-5,11-12,14-15H2,1H3/t20-,22-/m0/s1
    Key: ZSDAQBWGAOKTSI-UNMCSNQZSA-N
  • CN([C@@H]1[C@H](CC2=CC=CC=C12)N3CCCC3)C(=O)CC4=CC(=CC=C4)[N+](=O)[O-]
Properties
C22H25N3O3
Molar mass 379.460 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Niravoline is a chemical compound with the formula C
22H
25N
3O
3.[1] It has diuretic and aquaretic effects and has been studied for its potential use for cerebral edema[2] and cirrhosis.[3]

It exerts its pharmacological effect as a

kappa opioid receptor agonist.[4]

References

  1. ^ CID 9821174 from PubChem
  2. PMID 9223533
    .
  3. PMID 10673065
    .
  4. ^ "Niravoline". NCI Thesaurus. National Cancer Institute.
Stub icon

This article about an organic compound is a stub. You can help Wikipedia by expanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=Niravoline&oldid=1201154014"