Nodular sclerosis
| Nodular sclerosis | |
|---|---|
 | |
| Nodular sclerosis. The distinct nodules on the cut surface of this lymph node strongly suggest the diagnosis. | |
| Specialty | Oncology  |
Nodular sclerosis (or "NSHL") is a form of
Hodgkin's lymphoma[1] that is the most common subtype of HL in developed countries. It affects females slightly more than males and has a median age of onset at ~28 years. It is composed of large tumor nodules with lacunar Reed–Sternberg cell (RS cells) surrounded by fibrotic collagen bands.[citation needed
]
The British National Lymphoma Investigation further categorized NSHL based upon Reed-Sternberg cells into "nodular sclerosis type I" (NS I) and "nodular sclerosis type II" (NS II), with the first subtype responding better to treatment.[2]
References
- PMID 17908180.
- ISBN 978-0-7817-1502-7.
External links
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