Nooglutyl

Source: Wikipedia, the free encyclopedia.
Nooglutyl
Names
IUPAC name
N-[(5-Hydroxy-3-pyridinyl)carbonyl]-L-glutamic acid
Systematic IUPAC name
(2S)-2-(5-Hydroxypyridine-3-carboxamido)pentanoic acid
Other names
Nooglutil
Identifiers
3D model (
JSmol
)
ChemSpider
UNII
  • InChI=1S/C11H12N2O6/c14-7-3-6(4-12-5-7)10(17)13-8(11(18)19)1-2-9(15)16/h3-5,8,14H,1-2H2,(H,13,17)(H,15,16)(H,18,19)/t8-/m0/s1
    Key: XFZGYOJFPGPYCS-QMMMGPOBSA-N
  • InChI=1/C11H12N2O6/c14-7-3-6(4-12-5-7)10(17)13-8(11(18)19)1-2-9(15)16/h3-5,8,14H,1-2H2,(H,13,17)(H,15,16)(H,18,19)/t8-/m0/s1
    Key: XFZGYOJFPGPYCS-QMMMGPOBBD
  • O=C(c1cncc(O)c1)N[C@H](C(=O)O)CCC(=O)O
Properties
C11H12N2O6
Molar mass 268.225 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Nooglutyl is a

Russian Academy of Medical Sciences as a potential treatment for amnesia.[1]

In animal models, it has a variety of central nervous system effects.[2][3][4][5]

Nooglutyl has some structural similarities to Picamilon (N-Nicotinoyl-GABA). Nooglutyl is N-5-HydroxyNicotinoyl-L-Glutamic acid.

References

  1. ^ Flekhter, Oxana B. (2000). "Nooglutil, Russian Academy of Medical Science". Current Opinion in Central & Peripheral Nervous System Investigational Drugs. 2 (4): 491–497.
  2. S2CID 6344628
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