Noxious stimulus

Source: Wikipedia, the free encyclopedia.

A noxious stimulus is a

A-delta and C- nerve fibers, as well as free nerve endings) throughout the nervous system
of an organism.

The ability to perceive noxious stimuli is a prerequisite for nociception, which itself is a prerequisite for nociceptive pain.[1] A noxious stimulus has been seen to drive nocifensive behavioral responses, which are responses to noxious or painful stimuli. These include reflexive, escape behaviors, to avoid harm to an organism's body.

Because of rare genetic conditions that inhibit the ability to perceive physical pain, such as congenital insensitivity to pain and anhydrosis (CIPA), noxious stimulation does not invariably lead to tissue damage.[1]

Noxious stimuli can either be

chemical (e.g. exposure to acid or irritant), or thermal (e.g. high or low temperatures
).

There are some types of tissue damage that are not detected by any

nociceptors
. The adequate stimuli of nociceptors are termed nociceptive stimuli.

References