Nyamiviridae
Nyamiviridae | |
---|---|
Virions of San Jacinto virus forming at infected cell's surface and virus genome | |
Virus classification | |
(unranked): | Virus |
Realm: | Riboviria |
Kingdom: | Orthornavirae |
Phylum: | Negarnaviricota
|
Class: | Monjiviricetes |
Order: | Mononegavirales |
Family: | Nyamiviridae |
Nyamiviridae is a family of
History
Nyamanini virus (NYMV) and Midway virus (MDWV) were first isolated in 1957 and 1966 respectively. NYMV has been isolated from cattle egrets (species
Structure
Nyamivirions are enveloped, with spherical geometries. Their diameters are around 100 to 130 nm. Nyamiviral genomes are linear, nonsegmented and bisegmented, and around 11.6 kbp in total length. The nyamiviral genome codes for six proteins.[2][5] Of these, only two have been assigned a function: the putative nucleocapsid protein and RNA-dependent RNA polymerase.
Life cycle
Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral GP glycoproteins to host receptors, which mediates clathrin-mediated endocytosis. Replication follows the negative stranded RNA virus replication model. Negative stranded RNA virus transcription, using polymerase stuttering is the method of transcription. The virus progeny are released by budding from the infected cells. Ticks and birds serve as the natural host.[2][5]
Taxonomy
The family contains the following genera:[4]
References
- PMID 29120298.
- ^ a b c "ICTV Report Nyamiviridae".
- PMID 28389807.
- ^ a b "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved 18 May 2021.
- ^ a b "Viral Zone". ExPASy. Retrieved 13 August 2015.