OX40 ligand

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tumor necrosis factor (ligand) superfamily, member 4 (tax-transcriptionally activated glycoprotein 1, 34kDa)
Identifiers
SymbolTNFSF4
Alt. symbolsTXGP1, OX-40L, gp34, CD252
Chr. 1 q25
Search for
StructuresSwiss-model
DomainsInterPro

OX40L is the

dendritic cells),[1] macrophages,[2] and activated B lymphocytes.[3]

The

Th2 immune response even in an environment with low levels of IL-4 cytokine.[1][8]

OX40L is also present on the surface of many non-immune cells, for example,

The surface expression of OX40L is induced by many

TNF-α, e.g. produced by mast cells,[11] IFN-γ[12] and PGE2 (prostaglandin E2).[13]

OX40L has also been designated CD252 (cluster of differentiation 252).[14]

Various

systemic lupus erythematosus has been reported.[15] No association with occurrence of atherosclerosis has been found.[16]

References

External links