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Group of proteins
Octamer transcription factors are a family of transcription factors which binds to the "ATTTGCAT" DNA sequence .[1] DNA-binding domain is a POU domain .
There are eight Octamer proteins in humans (Oct1–11),embryonic development.
[3] Oct-6 expression is confined to embryonic stem cells and the developing nervous system and skin, while Oct-11 is also involved in skin differentiation.
[3]
Human Oct proteins References
. ^ Oct-5 and Oct-10 are not found in humans, while Oct-3 and Oct-4 were identified as the same protein.
^ .
External links
(1) Basic domains
(1.1) Basic leucine zipper (bZIP )(1.2) Basic helix-loop-helix (bHLH
)
Group A Group B Group CPAS Group D Group E Group F
(1.3) bHLH-ZIP (1.4) NF-1 (1.5) RF-X (1.6) Basic helix-span-helix (bHSH)
(2) Zinc finger DNA-binding domains
(2.1) Nuclear receptor (Cys4 )
subfamily 1 subfamily 2 subfamily 3 subfamily 4 subfamily 5 subfamily 6 subfamily 0
(2.2) Other Cys4 (2.3) Cys2 His2 (2.4) Cys6 (2.5) Alternating composition (2.6) WRKY
(4) β-Scaffold factors with minor groove contacts
(0) Other transcription factors
