Orthopoxvirus inclusion bodies
Orthopoxvirus inclusion bodies are aggregates of stainable protein produced by poxvirus
virions in the cell nuclei and/or cytoplasm of epithelial cells in humans. They are important as sites of viral replication.[1][2]
Morphology
Morphologically there are two types of Orthopoxvirus inclusion bodies, Type-A inclusion bodies and Guarnieri bodies. Type-A inclusion bodies are found only in certain poxviruses like
virions by electron microscopy.[citation needed
]
Guarnieri bodies are named for Giuseppe Guarnieri, (1856-1918) an Italian physician who first described them.[5]
References
- PMID 22438543.
- ^ Fenner, F., Witte, K.R., and Dumbell, K.R. The Orthopoxviruses. Academic Press, San Diego, 1989.
- S2CID 33135261.
- PMID 16200143.
- ISBN 0-7817-5443-7.