Oxetacaine

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Oxetacaine
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Oral, topical
ATC code
Pharmacokinetic data
Elimination half-life1 hour
Identifiers
  • 2,2'-(2-hydroxyethylimino)bis [N-(1,1-dimethyl-2- phenylethyl)-N-methylacetamide]
JSmol)
  • O=C(N(C(C)(C)Cc1ccccc1)C)CN(CCO)CC(=O)N(C(Cc2ccccc2)(C)C)C
  • InChI=1S/C28H41N3O3/c1-27(2,19-23-13-9-7-10-14-23)29(5)25(33)21-31(17-18-32)22-26(34)30(6)28(3,4)20-24-15-11-8-12-16-24/h7-16,32H,17-22H2,1-6H3 checkY
  • Key:FTLDJPRFCGDUFH-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Oxetacaine (

INN, also known as oxethazaine) is a potent local anesthetic. It is administered orally (usually in combination with an antacid) for the relief of pain associated with peptic ulcer disease or esophagitis. One example of such a product is Mucaine Gel, indicated for "rapid and effective relief in gastritis, esophagitis, hiatus hernia, heartburn of pregnancy and peptic ulcer".[1] It is also used topically in the management of hemorrhoid pain. Oral oxetacaine preparations are available in several countries, including India, South Africa, Japan, Taiwan and Brazil
, but not the United States. Unlike most local anesthetics, oxetacaine does not break down under strongly acidic conditions.[2]

References

  1. ^ "Mucaine Gel". Pfizer.com. Pfizer. Retrieved 6 October 2022.
  2. S2CID 39641018
    .

External links