Oxilorphan

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Oxilorphan
Clinical data
ATC code
  • None
Identifiers
  • (-)-17-(Cyclopropylmethyl)-morphinan-3,14-diol
JSmol)
  • Oc3ccc4C[C@H]1N(CC[C@@]2(CCCC[C@@]12O)c4c3)CC5CC5
  • InChI=1S/C20H27NO2/c22-16-6-5-15-11-18-20(23)8-2-1-7-19(20,17(15)12-16)9-10-21(18)13-14-3-4-14/h5-6,12,14,18,22-23H,1-4,7-11,13H2/t18-,19+,20-/m1/s1 checkY
  • Key:STBZIDOIKQNFCQ-HSALFYBXSA-N checkY
  (verify)

Oxilorphan (

opioid addiction, but was not developed commercially.[6] The KOR agonist effects of oxilorphan are associated with dysphoria, which combined with its hallucinogenic effects, serve to limit its clinical usefulness; indeed, many patients who experienced these side effects refused to take additional doses in clinical trials.[7]

See also

References

  1. ISBN 978-1-4757-2085-3
    .
  2. PMID 237112
    .
  3. S2CID 2819499
    .
  4. ISBN 978-0-08-058353-2
    .
  5. PMID 6131829
    .
  6. PMID 13984
    .
  7. ISBN 9780309024174
    .



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