Oxo-Diels–Alder reaction
| Oxo-Diels–Alder reaction | |
|---|---|
| Named after | Otto Diels Kurt Alder |
| Reaction type | Cycloaddition |
| Identifiers | |
| RSC ontology ID | RXNO:0000310 |
An oxo-Diels–Alder reaction (also called an oxa-Diels–Alder reaction) is an organic reaction and a variation of the Diels–Alder reaction in which a suitable diene reacts with an aldehyde to form a dihydropyran ring. This reaction is of some importance to synthetic organic chemistry.
The oxo-DA reaction was first reported in 1949[1] using a methylpentadiene and formaldehyde as reactants.
Asymmetric oxo-DA reactions (including catalytic reactions) are well known.[2] Many strategies rely on coordinating a chiral Lewis acid
to the carbonyl group.
See also
- Aza Diels–Alder reaction
- Imine Diels–Alder reaction