Palisaded neutrophilic and granulomatous dermatitis

Source: Wikipedia, the free encyclopedia.
Palisaded neutrophilic and granulomatous dermatitis
SpecialtyDermatology

Palisaded neutrophilic and granulomatous dermaititis (PNGS) is usually associated with a well-defined connective tissue disease, lupus erythematosus or rheumatoid arthritis most commonly, and often presents with eroded or ulcerated symmetrically distributed umbilicated papules or nodules on the elbows.[1][2]

Signs and symptoms

Typical clinical manifestations include erythematous to violaceous plaques that are symmetrically distributed, skin-colored linear cords involving the lateral trunks, and skin-colored or erythematous papules with crusting, perforation, or umbilication.[3]

Causes

Palisaded neutrophilic and granulomatous dermaititis is associated with subacute

Treatment

The underlying illness is the main focus of PNGD treatment. Up to 20% of patients may experience spontaneous resolution of the lesions.

Topical corticosteroids, NSAIDs (non-steroidal anti-inflammatory drugs), dapsone, prednisone, colchicine, oral tacrolimus, and TNF inhibitors are among the available treatment options.[3]

See also

  • Skin lesion
  • List of cutaneous conditions

References

Further reading

External links