Pancreatic juice
 | This article needs additional citations for verification. (April 2012) |
| Pancreatic juice | |
|---|---|
| Identifiers | |
| MeSH | D010189 |
| FMA | 62973 |
| Anatomical terminology | |
Pancreatic juice is a liquid secreted by the
Pancreatic juice is
Pancreatic juice secretion is principally regulated by the
The release of these hormones into the blood is stimulated by the entry of the acidic chyme into the duodenum. Their coordinated action results in the secretion of a large volume of pancreatic juice, which is alkaline and enzyme-rich, into the duodenum. The pancreas also receives autonomic innervation. The blood flow into pancreas is regulated by sympathetic nerve fibers, while parasympathetic neurons stimulate the activity of acinar and centroacinar cells.
Pancreatic secretion is an aqueous solution of bicarbonate originating from the duct cells and enzymes originating from the acinar cells. The bicarbonate assists in neutralising the low pH of the chyme coming from the stomach, while the enzymes assist in the breakdown of the proteins, lipids and carbohydrates for further processing and absorption in the intestines. Secretin-stimulated pancreatic juice can be collected during endoscopy and provides an important source for diagnostic biomarkers, allowing detection of pancreatic pathology, especially cancer not yet visible on medical imaging..[2]
Pancreatic juice is secreted into the duodenum through duodenal papillae. Some individuals have also an accessory duct, named accessory pancreatic duct, which may be functional (that is, it also empties the contents of the exocrine pancreas into the duodenum) or non-functional.
External links
- "Pancreatic juice" at Dorland's Medical Dictionary
- Nosek, Thomas M. "Section 6/6ch4/s6ch4_18". Essentials of Human Physiology. Archived from the original on 2016-03-24.
References
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