Papilloma

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Papilloma
Intraductal papilloma of breast, H&E, 10x
SpecialtyOncology Edit this on Wikidata

A papilloma (plural papillomas or papillomata) (

fronds. In this context, papilla
refers to the projection created by the tumor, not a tumor on an already existing papilla (such as the nipple).

When used without context, it frequently refers to infections (

carcinogenic.[2][3]
There are, however, a number of other conditions that cause papilloma, as well as many cases in which there is no known cause.

Signs and symptoms

HPV6 pedunculated papilloma behind the uvula and HPV6 sessile papilloma next to the uvula
HPV6 pedunculated papilloma removed from behind the uvula using a laser

A benign papillomatous tumor is derived from epithelium, with cauliflower-like projections that arise from the mucosal surface. It may appear white or normal colored. It may be

sessile. The average size is between 1–5 cm. Neither sex is significantly more likely to develop them. The most common site is the palate-uvula
area followed by tongue and lips. Durations range from weeks to 10 years.

Presence of HPV

Immunoperoxidase stains have identified antigens of the human papillomavirus (HPV) types 6 and 11 in approximately 50% of cases of squamous cell papilloma.[8]

Prognosis

There is no evidence that papillomas are

premalignant
.

Differential diagnosis

  • Intraoral
    verruca vulgaris
    ,
  • Condyloma acuminatum
    , and
  • Focal epithelial hyperplasia
    .

Note: differentiation is done accurately by microscopic examination only.

Treatment

With conservative surgical excision, recurrence is rare.[citation needed]

See also

References

  1. ^ "papilloma" at Dorland's Medical Dictionary
  2. ^
    S2CID 1451343
    .
  3. ^
    S2CID 10042384
    .
  4. ^
    S2CID 24219797
    .
  5. ^ "Human papillomavirus (HPV) and cervical cancer". WHO. June 2016. Archived from the original on 5 August 2016.
  6. NCBI. {{cite book}}: |work= ignored (help
    )
  7. ^ "Warts: Overview" (Updated ed.). U.S. National Library of Medicine. 7 November 2019 [30 July 2014]. Archived from the original on 10 September 2017. Retrieved 7 February 2021. {{cite journal}}: Cite journal requires |journal= (help)
  8. ISSN 1532-0650
    .

External links

Look up papilloma in Wiktionary, the free dictionary.
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