para-Chloroamphetamine

Source: Wikipedia, the free encyclopedia.
Not to be confused with para-Chloromethamphetamine.
para-Chloroamphetamine
Clinical data
Other namesPCA; 4-Chloroamphetamine; 4-CA
Legal status
Legal status
  • DE: NpSG (Industrial and scientific use only)
  • UK: Class A
Identifiers
  • 1-(4-Chlorophenyl)propan-2-amine
JSmol)
  • Clc1ccc(cc1)CC(N)C
  • InChI=1S/C9H12ClN/c1-7(11)6-8-2-4-9(10)5-3-8/h2-5,7H,6,11H2,1H3 checkY
  • Key:WWPITPSIWMXDPE-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

para-Chloroamphetamine (PCA), also known as 4-chloroamphetamine (4-CA), is a

6-hydroxydopamine is used to kill dopaminergic neurons.[2][3][4][5]

para-Chloroamphetamine has been detected as an apparent designer drug,[6] along with the related 3-chloroamphetamine, which is even more potent as a releaser of dopamine and serotonin but slightly less neurotoxic.[7][8][9][10][11]

The closely related N-methylated derivative, para-chloromethamphetamine (CMA), which is metabolized to para-chloroamphetamine in vivo, has neurotoxic properties as well.

Legal status

China

As of October 2015, 4-CA is a controlled substance in China.[12]

See also

References

  1. PMID 3707603
    .
  2. S2CID 1068793
    .
  3. PMID 80243
    .
  4. PMID 7682129
    .
  5. PMID 8602894
    .
  6. PMID 21513613
    .
  7. PMID 5029422
    .
  8. PMID 303437
    .
  9. PMID 474143
    .
  10. S2CID 41833796
    .
  11. PMID 579062
    .
  12. ^ "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Archived from the original on 1 October 2015. Retrieved 1 October 2015.
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