Paul Greengard

Source: Wikipedia, the free encyclopedia.
Paul Greengard
Scientific career
Fieldsneuroscience
InstitutionsRockefeller University
ThesisSome relationships between action potential, oxygen consumption and coenzyme content in degenerating peripheral axons (1954)
Doctoral advisorHaldan Keffer Hartline

Paul Greengard (December 11, 1925 – April 13, 2019) was an American

Nobel Prize for Physiology or Medicine for their discoveries concerning signal transduction in the nervous system. He was Vincent Astor Professor at Rockefeller University,[2] and served on the Scientific Advisory Board of the Cure Alzheimer's Fund, as well as the Scientific Council of the Brain & Behavior Research Foundation. He was married to artist Ursula von Rydingsvard
.

Biography

Greengard was born in New York City, the son of Pearl (née Meister) and Benjamin Greengard, a vaudeville comedian. His older sister was actress

Irene Kane, who later became a writer by the name of Chris Chase; she died in 2013, aged 89. Their mother died in childbirth[3] and their father remarried in 1927.[4] The Greengard siblings' parents were Jewish, but their stepmother was Episcopalian. He and his sister were "brought up in the Christian tradition".[5]

During

Hamilton College where he graduated in 1948 with a bachelor's degree in mathematics and physics. He decided against graduate school in physics because most post-war physics research was focusing on nuclear weapons, and instead became interested in biophysics
.

Greengard began his graduate studies at Johns Hopkins University in the lab of Haldan Keffer Hartline. Inspired by a lecture by Alan Hodgkin, Greengard began work on the molecular and cellular function of neurons. He received his PhD in 1953 and began postdoctoral work at the University of London, Cambridge University, and the University of Amsterdam.[6][3] Greengard then became director of the Department of Biochemistry at the Geigy Research Laboratories.

After leaving Geigy in 1967, he worked briefly at the

The Rockefeller University.[citation needed
]

He died on April 13, 2019.[8][9]

Research

Greengard's research focused on events inside the neuron caused by

DARPP-32.[10]

Family

Greengard had two sons from his first marriage, Claude and

In 1985, Greengard married sculptor Ursula von Rydingsvard.[13]

Discrimination complaints

In February 2018, a federal jury in the Southern District of New York found The Rockefeller University liable for discrimination based on race and national origin that occurred in 2007 in the lab of, and under the supervision of, Greengard.[14]

Pearl Meister Greengard Prize

Paul Greengard used his Nobel Prize honorarium to help fund the

award for women scientists. The award is named after his mother, who died during childbirth.[3] It was established in 2004 to shine a spotlight on exceptional women in science, since, as Greengard observed, "[women] are not yet receiving awards and honors at a level commensurate with their achievements."[15] The annual prize is awarded to an outstanding woman conducting biomedical research.[16]

Awards and honors

See also

References

  1. ^ "MetLife Foundation Awards for Medical Research in Alzheimer's Disease" (PDF). Archived from the original (PDF) on 13 October 2018.
  2. ^ "Paul Greengard profile". Rockefeller University. Archived from the original on 2008-09-22. Retrieved 2008-09-28.
  3. ^ a b c "The Academy Remembers President's Council Member, Dr. Paul Greengard". The New York Academy of Sciences. 16 April 2019. Retrieved 9 May 2019.
  4. ^ Dreifus, Claudia (September 26, 2006). "He Turned His Nobel Into a Prize for Women". The New York Times.
  5. ^ Profile of Paul Greengard, nobelprize.org; accessed December 28, 2013.
  6. ^ a b "Paul Greengard, PhD". The Michael J. Fox Foundation. Retrieved 9 May 2019.
  7. ^ "The Michael J. Fox Foundation and The Michael Stern Parkinson's Research Foundation Join Forces to Accelerate Novel Ideas in Parkinson's Research". The Michael J. Fox Foundation. 30 June 2015. Retrieved 9 May 2019.
  8. ^ Gellene D (14 April 2019). "Paul Greengard, 93, Nobel Prize-Winning Neuroscientist, Is Dead". The New York Times. Retrieved 9 May 2019.
  9. ^ "Pioneering neuroscientist and Nobel laureate Paul Greengard dies at 93". Retrieved 14 April 2019.
  10. ^ "Press Release: The Nobel Prize in Physiology or Medicine 2000". NobelPrize.org. 9 October 2000. Retrieved 9 May 2019.
  11. Daily News
    . Retrieved May 31, 2011.
  12. ^ "Leslie Greengard". www.nasonline.org. Retrieved 2022-02-10.
  13. ^ Smith, Harrison. "Paul Greengard, Nobel laureate who showed how nerve cells communicate, dies at 93". Washington Post. Retrieved 10 January 2021.
  14. ^ "$2.25 Million Jury Verdict in Race/National Origin Discrimination Case Against Rockefeller University". Blhny. 28 February 2018. Retrieved 9 May 2019.
  15. ^ Betsy Hanson (December 17, 2004). "The Birth of an Award". Benchmarks. Archived from the original on February 7, 2012. Retrieved 2008-09-28.
  16. ^ Dreifus, Claudia (September 26, 2006). "He Turned His Nobel Into a Prize for Women". New York Times. Retrieved September 26, 2006.
  17. ^ "Paul Greengard". National Academy of Sciences. Retrieved 9 May 2019.
  18. ^ "Paul Greengard". American Academy of Arts & Sciences. Retrieved 2022-02-10.
  19. ^ "Daniel Giraud Elliot Medal". National Academy of Sciences. Retrieved 16 February 2011.
  20. ^ "APS Member History". search.amphilsoc.org. Retrieved 2022-02-10.
  21. American Academy of Achievement
    .
  22. ^ "Premi e riconoscimenti - Lauree Honoris Causa" (in Italian). Retrieved 27 January 2018.
  23. ^ "Golgi Medal Award - Washington" (in Italian). Retrieved 27 January 2018.
  24. ^ "Gruppe 7: Medisinske fag" (in Norwegian). Norwegian Academy of Science and Letters. Archived from the original on 27 September 2011. Retrieved 7 October 2010.

Sources

  • Les Prix Nobel. 2001. The Nobel Prizes 2000, Editor Tore Frängsmyr, Nobel Foundation: Stockholm.

External links