Paul Janssen
Paul Adriaan Jan Janssen | |
---|---|
Janssen Pharmaceutica | |
Spouse | Dora Arts |
Parent(s) | Constant Janssen Margriet Fleerackers |
Paul Adriaan Jan, Baron Janssen (12 September 1926 – 11 November 2003) was a Belgian physician. He was the founder of
Early life and education
Paul Janssen was the son of Constant Janssen and Margriet Fleerackers.
He attended secondary school at the
On 16 April 1957, he married Dora Arts.
Career
During his military service and until 1952, he worked at the Institute of Pharmacology of the
With a loan of fifty thousand
In 1956, Janssen received his
On 11 February 1958 he developed
In 1959, Janssen synthesized the potent opioid fentanyl based on SAR studies of meperidine.[citation needed] In the 1970s, he would improve upon the potency of fentanyl with the synthesis of Carfentanil.
In 1985, Janssen Pharmaceutical became the first Western pharmaceutical company to establish a factory in the People's Republic of China (
Altogether Janssen and his cadre of scientists discovered more than eighty new medications, four of which are on the
In 1991, he was elevated to the Belgian nobility by King Baudouin receiving the title of Baron.[citation needed]
Death
Janssen died in Rome in 2003, while attending the celebration of the 400th anniversary of the founding of the Pontifical Academy of Sciences, of which he had been a member since 1990.[14]
Popularity polls
- In 2005 he finished as runner up, after Father Damien, in the poll for The Greatest Belgian organized by the regional Flemish television.[15]
- On Wednesday 22 October 2008, Paul Janssen was awarded the title of Most Important Belgian Scientist, an initiative of the Eos magazine.[16]
See also
- Gedeon Richter Ltd.
- Gairdner Foundation International Award
- Tibotec
- Rega Institute for Medical Research
References
- ^ Paul Lewi, Obituary of Dr Paul Janssen (1926–2003), Drug Discovery Today, Volume 9, Issue 10, 15 May 2004, Pages 432–433
- ^ Dr. Paul Janssen, 77, Dies; Founder of a Drug Company - website of the newspaper The New York Times
- LA Times
- ^ I. Oransky, Paul Janssen, The Lancet, Volume 363, Issue 9404, Pages 251–251
- ^ B. Granger, S. Albu, The Haloperidol Story, Annals of Clinical Psychiatry (after 1 January 2004), Volume 17, Number 3, Number 3/July–September 2005, pp. 137–140(4)
- S2CID 20490363. Retrieved 7 May 2011.
- S2CID 7720401.
- ^ "W. Royce Hawkins, M.D., John F. Zieglschmid, M.D., Clinical aspects of crew health". Lsda.jsc.nasa.gov. Archived from the original on 23 February 2012. Retrieved 12 March 2012.
- ^ "Apollo Medical Kits". History.nasa.gov. Retrieved 12 March 2012.
- ^ Magiels G, Paul Janssen. Pionier in farma en in China, Houtekiet, 2005
- ^ molmo.be Archived 31 July 2009 at the Wayback Machine
- ^ Yven Van Herrewege, Guido Vanham, Jo Michiels, Katrien Fransen, Luc Kestens, Koen Andries, Paul Janssen, and Paul Lewi, A Series of Diaryltriazines and Diarylpyrimidines Are Highly Potent Nonnucleoside Reverse Transcriptase Inhibitors with Possible Applications as Microbicides, Antimicrob Agents Chemother. 2004 October; 48(10): 3684–3689
- ^ "New AIDS Drug Discoveries To Battle Drug-Resistant HIV Strains". Sciencedaily.com. 20 August 2002. Retrieved 12 March 2012.
- ^ Neuropsychopharmacology. "Thomas A Ban, Paul Adriaan Jan Janssen, 1926–2003, Neuropsychopharmacology (2004) 29, 1579–1580". Nature.com. Retrieved 12 March 2012.
- ^ "De Grootste Belg". De Standaard (in Dutch). Retrieved 4 October 2011.
- ^ "Most Important Belgian Scientist". Picture.belga.be. 22 October 2008. Archived from the original on 20 February 2012. Retrieved 12 March 2012.
Further reading
- Lewi, Paul J., Successful Pharmaceutical Discovery: Paul Janssen's Concept of Drug Research, R&D Management, Vol. 37, Issue 4, pp. 355–362, September 2007.
- van Gestel S, Schuermans V, Thirty-three years of drug discovery and research with Dr. Paul Janssen, Drug Development Research, Volume 8, Issue 1–4, pp. 1–13.
- Geerdt Magiels; Joos Horsten (2004). Paul Janssen: pionier in farma en in China. Houtekiet. ISBN 9789052408279.
- Drug Design with Dr. Paul Janssen
- In memory of Dr. Paul Janssen
- Rory Watson, Paul Janssen, BMJ 2003;327;1290
- 1996 Australia Prize