Pentameric protein

A pentameric protein is a

Five sub-units come together to form a channel. Each channel consist of two alpha chain, one beta, one gamma and one delta chain. These five chains assemble together (along with certain receptors like protons or acetylcholine) forming the structure of the channel.^[1] A ligand-gated ion channel on the post-synaptic junction of the muscle-end plate is an example of such a channel. They are acetylcholine-operated ion channels, which means that acetylcholine brings about a conformational change. The channel allows the free movement of the cations like Na and K when acetylcholine binds to its receptors.

Viral capsids

Many

Protein enclosing bacterial organelles carboxysome is also made up of pentameric protein.^[3]

Major histocompatibility complex (MHC) pentamers

Synthetic pentameric proteins include MHC pentamers, a type of

• Pentamer

References