Perineurium
| Perineurium | |
|---|---|
 Transverse section of human tibial nerve (perineurium labeled at upper right) | |
 Nerve structure | |
| Identifiers | |
| TA98 | A14.2.00.015 |
| TA2 | 6156 |
| FMA | 52585 |
| Anatomical terminology | |
The perineurium is a protective sheath that surrounds a nerve fascicle.[1] This bundles together axons targeting the same anatomical location.[1] The perineurium is composed from fibroblasts.[2]
In the
Structure
The perineurium is composed of
The perineurium is a smooth, transparent tubular membrane which may be easily separated from the fibers it encloses. In contrast, the epineurium is a tough and mechanically resistant tissue which is not easily penetrated by a needle.
Clinical importance
The perineurium, as the epineurium, has a clinical importance following a trauma, like a fracture. A sort of lesion called axonotmesis[3] can happen, where the axon of the nerve is damaged while the integrity of the perineurium and epineurium is preserved. In that case, they will be a loss of neural transmission which will be causing a diminished response in the distal part of the nerve. The axon will be able to regenerate itself at a rate of 3 cm per month, generally indicating a return to a physiological state in roughly three months.
See also
- Connective tissue in the peripheral nervous system
- Endoneurium
- Epineurium
- Nerve fascicle
References
- ^ ISBN 1-5866-3097-0.
- ISBN 978-0-7216-9491-7, retrieved 2020-11-18
- ^ Netter, Frank. Netter's Orthopaedics.
External links
- Histology image: 1_03 at the University of Oklahoma Health Sciences Center - "Peripheral nerve"
- Anatomy photo: nervous/pns/nerve1/nerve2 - Comparative Organology at University of California, Davis - "PNS, nerve (LM, Low)"
- Histology image: 21401loa – Histology Learning System at Boston University
- Diagram at Howard
- Histology at ucla.edu
