Pheneturide

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Pheneturide
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • (RS)-N-Carbamoyl-2-phenyl-butanamide
JSmol)
ChiralityRacemic mixture
  • O=C(N)NC(=O)C(c1ccccc1)CC
  • InChI=1S/C11H14N2O2/c1-2-9(10(14)13-11(12)15)8-6-4-3-5-7-8/h3-7,9H,2H2,1H3,(H3,12,13,14,15) checkY
  • Key:AJOQSQHYDOFIOX-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Pheneturide (

ureide class.[2][3] Conceptually, it can be formed in the body as a metabolic degradation product from phenobarbital. It is considered to be obsolete[4] and is now seldom used.[5] It is marketed in Europe, including in Poland, Spain and the United Kingdom.[6] Pheneturide has a similar profile of anticonvulsant activity and toxicity relative to phenacemide.[7][8] As such, it is only used in cases of severe epilepsy when other, less-toxic drugs have failed.[8] Pheneturide inhibits the metabolism and thus increases the levels of other anticonvulsants, such as phenytoin.[5][6]

See also

References

  1. ISBN 978-3-7692-2114-5
    .
  2. ISBN 978-1-4757-2085-3
    .
  3. PMID 10423278
    .
  4. ISBN 978-0-7817-2321-3
    .
  5. ^
    ISBN 978-94-011-6223-4
    .
  6. ^
    ISBN 978-0-323-14395-0
    .
  7. ISBN 978-3-0348-7161-7
    . Retrieved 3 September 2016.
  8. ^
    ISBN 978-1-4831-9294-9
    .