Phenindione

Phenindione

Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy category	AU: D Passes into breast milk
Routes of administration	Oral
ATC code	B01AA02 (WHO)
Pharmacokinetic data
Protein binding	88%
Elimination half-life	5 to 10 hours
Identifiers
IUPAC name 2-phenyl-1H-indene-1,3(2H)-dione
JSmol)	Interactive image
SMILES O=C2c1ccccc1C(=O)C2c3ccccc3
InChI InChI=1S/C15H10O2/c16-14-11-8-4-5-9-12(11)15(17)13(14)10-6-2-1-3-7-10/h1-9,13H Y Key:NFBAXHOPROOJAW-UHFFFAOYSA-N Y
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Phenindione is an anticoagulant which functions as a Vitamin K antagonist.

Phenindione was introduced in the early 1950s. It acts similar to warfarin, but it has been associated with hypersensitivity reactions, so it is rarely used and warfarin is preferred.^[1][2]

References