Phenyltoloxamine

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Phenyltoloxamine
Clinical data
AHFS/Drugs.comInternational Drug Names
Pregnancy
category
  • C (US)
Routes of
administration		Oral
ATC code
  • None
Identifiers
  • 2-(2-Benzylphenoxy)-N,N-dimethylethanamine
JSmol)
  • O(c1ccccc1Cc2ccccc2)CCN(C)C
  • InChI=1S/C17H21NO/c1-18(2)12-13-19-17-11-7-6-10-16(17)14-15-8-4-3-5-9-15/h3-11H,12-14H2,1-2H3 checkY
  • Key:IZRPKIZLIFYYKR-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Phenyltoloxamine is an antihistamine with sedative and analgesic effects.[1][2] It is available in combination with other drugs such as paracetamol (acetominophen).[3]

Common use

Phenyltoloxamine is widely used in preparations as an enhancing

cough suppressant usually with codeine, and sometimes by itself or in addition to dextromethorphan as it, like diphenhydramine
, possesses antitussive action of its own and is particularly useful in semi-productive coughs because of its moderate drying action.

Phenyltoloxamine is used in combination with

salicylates
and other drugs in proprietary preparations available over the counter for backache, muscle strains and similar conditions.

Adverse effects

Common

adverse effects are those associated with most anticholinergics, with effects being more pronounced in children and the elderly.[medical citation needed
]

Availability

Though it is rare in several

developing world
.

In the past it was not a

acetaminophen it is generally over the counter
.

Phenyltoloxamine combinations are sold under wide variety of preparations, brand names and dosages around the world:

  • Aceta-Gesic, Ed-Flex, Dologesic, Duraxin, Flextra-650, Novagesic, Pain-gesic, Phenylgesic - North America
  • Codipront - Europe/South America
  • Codivis - Israel

See also

References

  1. Drugbank
    .
  2. PMID 14370508
    .
  3. ^ "Phenyltoloxamine-acetaminophen oral". WebMD.
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