Phytochemistry

Source: Wikipedia, the free encyclopedia.

Phytochemistry is the study of phytochemicals, which are chemicals derived from plants. Phytochemists strive to describe the structures of the large number of secondary metabolites found in plants, the functions of these compounds in human and plant biology, and the biosynthesis of these compounds. Plants synthesize phytochemicals for many reasons, including to protect themselves against insect attacks and plant diseases. The compounds found in plants are of many kinds, but most can be grouped into four major biosynthetic classes: alkaloids, phenylpropanoids, polyketides, and terpenoids.

Phytochemistry can be considered a subfield of botany or chemistry. Activities can be led in botanical gardens or in the wild with the aid of ethnobotany. Phytochemical studies directed toward human (i.e. drug discovery) use may fall under the discipline of pharmacognosy, whereas phytochemical studies focused on the ecological functions and evolution of phytochemicals likely fall under the discipline of chemical ecology. Phytochemistry also has relevance to the field of plant physiology.

Techniques

Techniques commonly used in the field of phytochemistry are

HPLC
, and LC-MS).

Phytochemicals

Many plants produce chemical compounds

chickweed.[2][3]

Many phytochemicals, including curcumin, epigallocatechin gallate, genistein, and resveratrol are pan-assay interference compounds and are not useful in drug discovery.[4][5]

Alkaloids

Glycosides

senna,[9] rhubarb, and Aloe.[10]

The

foxglove and lily of the valley. They include digoxin and digitoxin which act as diuretics.[11]

Polyphenols

Polyphenols of several classes are widespread in plants, including anthocyanins, phytoestrogens, and tannins.[13] Polyphenols are secondary metabolites produced by almost every part of plants, including fruits, flowers, leaves and bark.[13]

Terpenes

vermifuge (anti-worm medicine).[16][17]

Genetics

Contrary to bacteria and fungi, most plant

Avena sativa, Cucurbitaceae, Arabidopsis, and momilactone diterpenes in Oryza sativa.[18]

References

  1. ^ "Angiosperms: Division Magnoliophyta: General Features". Encyclopædia Britannica (volume 13, 15th edition). 1993. p. 609.
  2. .
  3. .
  4. .
  5. .
  6. ^ a b "Atropa Belladonna" (PDF). The European Agency for the Evaluation of Medicinal Products. 1998. Archived from the original (PDF) on 17 April 2018. Retrieved 26 February 2017.
  7. S2CID 25434984
    .
  8. ^ "Nicotinic acetylcholine receptors: Introduction". IUPHAR Database. International Union of Basic and Clinical Pharmacology. Archived from the original on 29 June 2017. Retrieved 26 February 2017.
  9. ^
    PMID 3671329
    .
  10. .
  11. ^ a b c "Active Plant Ingredients Used for Medicinal Purposes". United States Department of Agriculture. Retrieved 18 February 2017.
  12. ^ "Digitalis purpurea. Cardiac Glycoside". Texas A&M University. Archived from the original on 2 July 2018. Retrieved 26 February 2017. The man credited with the introduction of digitalis into the practice of medicine was William Withering.
  13. ^ a b "Flavonoids". Micronutrient Information Center, Linus Pauling Institute, Oregon State University. 1 February 2016. Retrieved 11 October 2023.
  14. JSTOR 27836252
    .
  15. .
  16. ^ a b c "Thymol (CID=6989)". NIH. Retrieved 26 February 2017. THYMOL is a phenol obtained from thyme oil or other volatile oils used as a stabilizer in pharmaceutical preparations, and as an antiseptic (antibacterial or antifungal) agent. It was formerly used as a vermifuge.
  17. ISSN 2160-3855
    .
  18. .