Plague vaccine

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Plague vaccine
Plague vaccine being administered
Vaccine description
TargetYersinia pestis
Vaccine typeAttenuated
Clinical data
AHFS/Drugs.comMicromedex Detailed Consumer Information
ATC code
Identifiers
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Plague vaccine is a vaccine used against Yersinia pestis to prevent the plague.[1] Inactivated bacterial vaccines have been used since 1890 but are less effective against the pneumonic plague, so live, attenuated vaccines and recombinant protein vaccines have been developed to prevent the disease.[2]

Plague immunization

The first plague vaccine was developed by bacteriologist

Bombay between 1897 and 1925, reducing the plague mortality by 50%-85%.[3][6]

A plague vaccine is used for an induction of active specific

immunity to plague in a susceptible organism after administration of a plague serum or plague immunological in people with an immediate risk of developing the disease.[7]

A systematic review by the

Cochrane Collaboration found no studies of sufficient quality to be included in the review, and were thus unable to make any statement on the efficacy of modern vaccines.[8]

References

  1. ^ Plague+Vaccine at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
  2. PMID 17652523
    .
  3. ^ a b "Waldemar Haffkine: The vaccine pioneer the world forgot". BBC News. 2020-12-11. Retrieved 2021-01-20.
  4. ^ a b "WALDEMAR MORDECAI HAFFKINE". Haffkine Institute. Archived from the original on 2015-09-24. Retrieved 2021-01-20.
  5. PMID 21122347
    .
  6. .
  7. ^ "WHO | Zoonotic Infections". www.who.int. Archived from the original on 22 March 2006. Retrieved 15 January 2022.
  8. PMID 10796565
    .