Pleomorphism (cytology)

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A micrograph showing cells with marked nuclear shape and size variation, a component of nuclear pleomorphism.

Pleomorphism is a term used in

benign cell types may also exhibit pleomorphism, e.g. neuroendocrine cells, Arias-Stella reaction
.

A rare type of rhabdomyosarcoma that is found in adults is known as pleomorphic rhabdomyosarcoma.[4]

Despite the prevalence of pleomorphism in human pathology, its role in disease progression is unclear. In

epithelial tissue, pleomorphism in cellular size can induce packing defects and disperse aberrant cells.[5]
But the consequence of atypical cell and nuclear morphology in other tissues is unknown.

See also

References