Propacetamol

Source: Wikipedia, the free encyclopedia.
Propacetamol
IV[1][2]
ATC code
Pharmacokinetic data
Elimination half-life2.4 hours [1]
ExcretionRenal
Identifiers
  • 4-(acetamido)phenyl N,N-diethylglycinate
JSmol)
  • CCN(CC)CC(=O)OC1=CC=C(C=C1)NC(=O)C
  • InChI=1S/C14H20N2O3/c1-4-16(5-2)10-14(18)19-13-8-6-12(7-9-13)15-11(3)17/h6-9H,4-5,10H2,1-3H3,(H,15,17)
  • Key:QTGAJCQTLIRCFL-UHFFFAOYSA-N
  (verify)

Propacetamol is a

esterification of paracetamol, and the carboxylic acid diethylglycine. This has the advantage of making it more water-soluble. It is used in post-operative care and is delivered by I.V.[2] It is given if the patient is unable to take oral or rectally delivered paracetamol and nonsteroidal anti-inflammatory drugs (NSAIDs) are contraindicated. The onset of analgesia from propacetamol is more rapid than paracetamol given orally.[3]
2 grams of propacetamol are equivalent to 1g of paracetamol.[4]

See also

References

  1. ^
    PMID 1633071
    .
  2. ^
    PMID 15367329
    .
  3. PMID 15790675
    .
  4. PMID 14756388
    .
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