Quinupramine

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Quinupramine
Clinical data
Routes of
administration		Oral
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Elimination half-life33 hours
Identifiers
  • (±)-11-quinuclidin-3-yl-5,6-dihydrobenzo[b][1]benzazepine
ECHA InfoCard
100.046.149 Edit this at Wikidata
Chemical and physical data
FormulaC21H24N2
Molar mass304.437 g·mol−1

Quinupramine (brand names Kevopril, Kinupril, Adeprim, Quinuprine) is a tricyclic antidepressant (TCA) used in Europe for the treatment of depression.[1][2]

Pharmacologically, quinupramine acts

D2 receptor.[3]

Clinically, quinupramine is reported to be stimulating similarly to imipramine, desipramine, and demexiptiline.[4] It can be inferred that its in vivo metabolites may have stronger effects on the reuptake of norepinephrine and/or serotonin than quinupramine itself.[citation needed]

References

  1. ISBN 3-88763-075-0
    .
  2. ISBN 978-3-527-31058-6
    .
  3. ^
    PMID 6098759
    .
  4. ISBN 0-306-47406-9
    .