RHD (gene)

Source: Wikipedia, the free encyclopedia.
RHD
Identifiers
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Ensembl
UniProt
RefSeq (mRNA)

NM_011270

RefSeq (protein)

NP_035400

Location (UCSC)Chr 1: 25.27 – 25.33 MbChr 4: 134.59 – 134.62 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Rh blood group, D antigen also known as Rh polypeptide 1 (RhPI) or cluster of differentiation 240D (CD240D) is a protein that in humans is encoded by the RHD gene.[5]

The RHD gene codes for the RhD

erythrocyte Rh complex is a heterotrimer of RhAG, RhD, and RhCE protein subunits.[7] RhAG is a functional ammonia transporter and is required for normal cell surface expression of RhD and RhCE. Patients who lack RhD/RhCE/RhAG on the surface of their erythrocytes have hemolytic anemia. Antibodies to the RhD protein can cause Rh disease
.

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000187010 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028825 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Rh blood group".
  6. PMID 17198846
    .
  7. .

Further reading

See also