Rauwolscine

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Rauwolscine
Rauwolscine_3D_BS
Clinical data
Routes of
administration		Oral
ATC code
  • none
Legal status
Legal status
  • In general: uncontrolled
Identifiers
  • 17α-hydroxy-20α-yohimban-16β-carboxylic acid methyl ester
ECHA InfoCard
100.004.553 Edit this at Wikidata
Chemical and physical data
FormulaC21H26N2O3
Molar mass354.450 g·mol−1
  • InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15+,17+,18+,19+/m1/s1 checkY
  • Key:BLGXFZZNTVWLAY-DIRVCLHFSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Rauwolscine, also known as isoyohimbine, α-yohimbine, and corynanthidine, is an

stereoisomer of yohimbine.[1] Rauwolscine is a central nervous system stimulant, a local anesthetic and a vague aphrodisiac.[1]

Rauwolscine acts predominantly as a

α2-adrenergic receptor antagonist.[2][3] It has also been shown to function as a 5-HT1A receptor partial agonist and 5-HT2A and 5-HT2B receptor antagonist.[4][5][6]

See also

References

  1. ^
    S2CID 4212268
    .
  2. PMID 6276200
    .
  3. PMID 18434433
    .
  4. PMID 8517875
    .
  5. S2CID 23251900
    .
  6. S2CID 28910390. Archived from the original
    on 2001-09-11.
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