Retinoid X receptor gamma

Source: Wikipedia, the free encyclopedia.
RXRG
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Ensembl
UniProt
RefSeq (mRNA)

NM_001256570
NM_001256571
NM_006917

NM_001159731
NM_009107

RefSeq (protein)

NP_001243499
NP_001243500
NP_008848

NP_001153203
NP_033133

Location (UCSC)Chr 1: 165.4 – 165.45 MbChr 1: 167.43 – 167.47 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Retinoid X receptor gamma (RXR-gamma), also known as NR2B3 (nuclear receptor subfamily 2, group B, member 3) is a nuclear receptor that in humans is encoded by the RXRG gene.[5][6]

Function

This gene encodes a member of the

vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[6]

See also

Interactions

Retinoid X receptor gamma has been shown to

interact with ITGB3BP.[7]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000143171 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000015843 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. PMID 8034312
    .
  6. ^ a b "Entrez Gene: RXRG retinoid X receptor, gamma".
  7. PMID 11713274
    .

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.