Retroposon
Retroposons are repetitive
reverse transcribed from any RNA
molecule.
Difference between retroposons and retrotransposons
In contrast to
transposons
).
Non-long terminal repeat (LTR) retrotransposons such as the human retroviruses, in addition, are packaged as viral particles (virions). Retrosequences are non-autonomous elements devoid of RT. They are retroposed with the aid of the machinery of autonomous elements, such as LINEs; examples are short interspersed nuclear elements (SINEs) or mRNA-derived retro(pseudo)genes.[2][3][4]
Gene duplications
Retroposition accounts for approximately 10,000 gene-duplication events in the human genome, of which approximately 2-10% are likely to be functional.[5] Such genes are called retrogenes and represent a certain type of retroposon.
Horizontal gene transfer
A classical event is the retroposition of a spliced pre-mRNA molecule of the c-Src gene into the proviral ancestor of the Rous sarcoma virus (RSV). The retroposed c-src pre-mRNA still contained a single intron and within RSV is now referred to as v-Src gene.[6]
References
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