Retrotransposon marker

Add links
Source: Wikipedia, the free encyclopedia.

Retrotransposon markers are components of DNA which are used as

plesiomorphic condition prior to integration in more distant taxa. The use of presence/absence analyses to reconstruct the systematic biology of mammals depends on the availability of retrotransposons that were actively integrating before the divergence of a particular species
.

Details

The analysis of

DNA sequence and morphological
data.

The reason for this is that retrotransposons are assumed to represent powerful noise-poor

derived character state at the respective locus
thus becomes possible as the absence of the introduced sequence can be with high confidence considered ancestral.

In combination, the low incidence of

plesiomorphic condition prior to integration in more distant taxa. The use of presence/absence analyses to reconstruct the systematic biology of mammals depends on the availability of retrotransposons that were actively integrating before the divergence of a particular species.[4]

Examples for

mammalian evolution.[9][10]

Inter-retrotransposons amplified polymorphisms (IRAPs) are alternative retrotransposon-based markers. In this method, PCR oligonucleotide primers face outwards from terminal retrotransposon regions. Thus, they amplify the fragment between two retrotransposon insertions. As retrotransposon integration patterns vary between genotypes, the number and size of the resulting amplicons can be used for differentiation of genotypes or cultivars, to measure genetic diversity or to reconstruct phylogenies.[11][12][13] SINEs, which are small in size and often integrate within or next to genes represent an optimal source for the generation of effective IRAP markers.[14]

References

  1. ^
    PMID 10655034
    .
  2. PMID 16140992
    .
  3. PMID 10369767
    .
  4. PMID 18629669. {{cite book}}: |journal= ignored (help
    )
  5. PMID 10468596
    .
  6. PMID 14561894
    .
  7. PMID 15249661
    .
  8. PMID 20668664
    .
  9. PMID 16515367
    .
  10. PMID 16785431
    .
  11. S2CID 28784368
    .
  12. PMID 10036780
    .
  13. PMID 11239612
    .
  14. S2CID 15776815
    .
Retrieved from "https://en.wikipedia.org/w/index.php?title=Retrotransposon_marker&oldid=1207899653"