Richard M. Durbin

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Richard Durbin

Durbin in 2008
Born
Richard Michael Durbin

(1960-12-30) 30 December 1960 (age 63)[15]
NationalityBritish
EducationHighgate School
Alma materUniversity of Cambridge (BA, PhD)
Known for
  • Biological Sequence Analysis[16]
Spouse
(m. 1996)
[15]
Awards
Scientific career
Fields
Institutions
John G. White[3]
Doctoral studentsEwan Birney[4]
Other notable students
Websitewww.gen.cam.ac.uk/directory/richard-durbin Edit this at Wikidata

Richard Michael Durbin

associate faculty member at the Wellcome Sanger Institute where he was previously a senior group leader.[24][25][26][27]

Education

Durbin was educated at

Career and research

Durbin's early work included developing the primary instrument software for one of the first

Biorad confocal microscope, alongside contributions to neural modelling.[31][32]

He then led the informatics for the Caenorhabditis elegans genome project,[33] and alongside Jean Thierry-Mieg developed the genome database AceDB, which evolved into the WormBase web resource. Following this he played an important role in data collection for and interpretation of the human genome sequence.[34]

He has developed numerous methods for computational

Ensembl,[39] and the gene family database TreeFam.[9]

More recently Durbin has returned to sequencing and has developed low coverage approaches to population genome sequencing, applied first to yeast,[40][41] and has been one of the leaders in the application of new sequencing technology to study human genome variation.[42][43] Durbin currently co-leads the international 1000 Genomes Project to characterise variation down to 1% allele frequency as a foundation for human genetics.

Awards and honours

Durbin was a joint winner of the

Fellow of the Royal Society (FRS) in 2004[17] and a member of the European Molecular Biology Organization (EMBO) in 2009. The Royal Society awarded its Gabor Medal to Durbin in 2017 for his contributions to computational biology.[44] In 2023 he received the International Prize for Biology
for his work on the Biology of Genomes.

Durbin's certificate of election for the Royal Society reads:

Durbin is distinguished for his powerful contribution to computational biology. In particular, he played a leading role in establishing the new field of bioinformatics. This allows the handling of biological data on an unprecedented scale, enabling genomics to prosper. He led the analysis of the C. elegans genome, and with Thierry-Mieg developed the database software AceDB. In the international genome project he led the analysis of protein coding genes. He introduced key computational tools in software and data handling. His Pfam database allowed the identification of domains in new protein sequences; it used hidden Markov models to which approach generally he brought rigour and which led to covariance models for RNA sequence.[45]

Personal life

Durbin is the son of James Durbin and is married to Julie Ahringer, a scientist at the Gurdon Institute. They have two children.[15]

References

  1. ^ "EMBO welcomes 66 leading life scientists as members". biochemist.org.
  2. ^ a b Richard M. Durbin publications indexed by Google Scholar Edit this at Wikidata
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  10. ^ "Heng Li Credits Durbin Pedigree in Accepting Franklin Award". bio-itworld.com. Archived from the original on 27 February 2013.
  11. PMID 14681378. Open access icon
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  17. ^ a b "Professor Richard Durbin FRS Fellow". London: Royal Society. Archived from the original on 19 November 2015.
  18. ^ anon. "Durbin, Richard". sanger.ac.uk. Retrieved 2 January 2019.
  19. Twitter Edit this at Wikidata
  20. ^ Richard M. Durbin at DBLP Bibliography Server Edit this at Wikidata
  21. ^ "Honorary Professors". Cambridge University Reporter. CXLV (5). University of Cambridge. 12 December 2014. Archived from the original on 15 March 2015.
  22. ^ Anon. "Durbin Group — Department of Genetics". gen.cam.ac.uk. Retrieved 2 January 2019.
  23. ^ Anon (27 September 2017). "Professor Richard Durbin — Department of Genetics". gen.cam.ac.uk. Retrieved 2 January 2019.
  24. ^ "Dr Richard Durbin – Wellcome Trust Sanger Institute". Archived from the original on 28 February 2012.
  25. ^ Durbin, Richard M.'s publications indexed by the Scopus bibliographic database. (subscription required)
  26. ^ Richard Durbin archive collection Richard Durbin entry in the Wellcome Library archive.
  27. ^ Richard M. Durbin publications from Europe PubMed Central
  28. ^ Richard M. Durbin's results at International Mathematical Olympiad
  29. ^ "The BioInformer nr. 1, 1997 – Interview with Dr. Richard Durbin". Archived from the original on 2 October 2011. Retrieved 30 July 2011.
  30. PMID 3704639
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  44. ^ "Gabor Medal - Gabor Medallist 2017". The Royal Society. 2017. Retrieved 10 October 2017.
  45. ^ "Library and Archive Catalogue". London: The Royal Society. Retrieved 14 November 2013.