SIB-1553A

Source: Wikipedia, the free encyclopedia.
SIB-1553A
Names
Preferred IUPAC name
4-{[2-(1-Methylpyrrolidin-2-yl)ethyl]sulfanyl}phenol
Identifiers
3D model (
JSmol
)
ChEMBL
ChemSpider
UNII
  • InChI=1S/C13H19NOS/c1-14-9-2-3-11(14)8-10-16-13-6-4-12(15)5-7-13/h4-7,11,15H,2-3,8-10H2,1H3
    Key: NVZGJSVPOOILDI-UHFFFAOYSA-N
  • InChI=1/C13H19NOS/c1-14-9-2-3-11(14)8-10-16-13-6-4-12(15)5-7-13/h4-7,11,15H,2-3,8-10H2,1H3
    Key: NVZGJSVPOOILDI-UHFFFAOYAV
  • OC1=CC=C(SCCC2CCCN2C)C=C1
Properties
C13H19NOS
Molar mass 237.36 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

SIB-1553A is a nicotinic acetylcholine receptor agonist that is selective for receptors with a β4 subunit. Administration of SIB-1553A improved memory and attention in a Parkinson's disease model.[1]

References

  1. S2CID 7060934
    .