Sodium/myo-inositol cotransporter
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SLC5A3
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| Location (UCSC) | Chr 21: 34.07 – 34.11 Mb | Chr 16: 91.86 – 91.88 Mb | |||||||
| PubMed search | [3] | [4] | |||||||
| View/Edit Human | View/Edit Mouse |
Sodium/myo-inositol cotransporter is a protein that in humans is encoded by the SLC5A3 gene.[5][6]
Expression of the myo-inositol transport protein is regulated by osmotic stress.[7]
See also
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000198743 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000089774 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- PMID 7789985.
- ^ "Entrez Gene: SLC5A3 solute carrier family 5 (inositol transporters), member 3".
- PMID 21209002.
Further reading
- Kwon HM, Yamauchi A, Uchida S, et al. (1992). "Cloning of the cDNa for a Na+/myo-inositol cotransporter, a hypertonicity stress protein". J. Biol. Chem. 267 (9): 6297–301. PMID 1372904.
- Berry GT, Mallee JJ, Blouin JL, Antonarakis SE (1996). "The 21q22.1 STS marker, VN02 (EST00541 cDNA), is part of the 3' sequence of the human Na+/myo-inositol cotransporter (SLC5A3) gene". Cytogenet. Cell Genet. 73 (1–2): 77–8. PMID 8646889.
- Mallee JJ, Atta MG, Lorica V, et al. (1998). "The structural organization of the human Na+/myo-inositol cotransporter (SLC5A3) gene and characterization of the promoter". Genomics. 46 (3): 459–65. PMID 9441750.
- Porcellati F, Hlaing T, Togawa M, et al. (1998). "Human Na(+)-myo-inositol cotransporter gene: alternate splicing generates diverse transcripts". Am. J. Physiol. 274 (5 Pt 1): C1215–25. S2CID 22626824.
- Rim JS, Atta MG, Dahl SC, et al. (1998). "Transcription of the Sodium/myo-Inositol Cotransporter Gene Is Regulated by Multiple Tonicity-responsive Enhancers Spread over 50 Kilobase Pairs in the 5′-Flanking Region". J. Biol. Chem. 273 (32): 20615–21. PMID 9685419.
- Hattori M, Fujiyama A, Taylor TD, et al. (2000). "The DNA sequence of human chromosome 21". Nature. 405 (6784): 311–9. PMID 10830953.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. PMID 14702039.
- Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions". Genome Res. 14 (9): 1711–8. PMID 15342556.
- Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. PMID 16344560.
- Thangaraju M, Gopal E, Martin PM, et al. (2007). "SLC5A8 triggers tumor cell apoptosis through pyruvate-dependent inhibition of histone deacetylases". Cancer Res. 66 (24): 11560–4. PMID 17178845.
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