SR-16435

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SR-16435
Identifiers
  • 1-[1-(9-bicyclo[3.3.1]nonanyl)piperidin-4-yl]-3H-indol-2-one
JSmol)
  • C1CC2CCCC(C1)C2N3CCC(CC3)N4C(=O)CC5=CC=CC=C54
  • InChI=1S/C22H30N2O/c25-21-15-18-5-1-2-10-20(18)24(21)19-11-13-23(14-12-19)22-16-6-3-7-17(22)9-4-8-16/h1-2,5,10,16-17,19,22H,3-4,6-9,11-15H2
  • Key:XVFXJQGBDPFCRF-UHFFFAOYSA-N

SR-16435 is a drug which acts as a potent partial agonist at both the μ-opioid receptor and nociceptin receptor. In animal studies it was found to be a potent analgesic, with results suggestive of reduced development of tolerance and increased activity against neuropathic pain compared to classic μ-selective agonists.[1][2][3]

See also

References