Sarcolemma

Source: Wikipedia, the free encyclopedia.
Sarcolemma
Skeletal muscle fibre, with sarcolemma labeled at upper left.
Details
LocationStriated muscle tissue
FunctionCell membrane
Identifiers
MeSHD012508
THH2.00.05.0.00003
Anatomical terminology

The sarcolemma (sarco (from sarx) from Greek; flesh, and lemma from Greek; sheath), also called the myolemma, is the

cardiomyocyte.[1][2]
It consists of a lipid bilayer and a thin outer coat of polysaccharide material (glycocalyx) that contacts the basement membrane. The basement membrane contains numerous thin collagen fibrils and specialized proteins such as laminin[3] that provide a scaffold to which the muscle fibre can adhere. Through transmembrane proteins in the plasma membrane, the actin skeleton inside the cell is connected to the basement membrane and the cell's exterior. At each end of the muscle fibre, the surface layer of the sarcolemma fuses with a tendon fibre, and the tendon fibres, in turn, collect into bundles to form the muscle tendons that adhere to bones.

The sarcolemma generally maintains the same function in muscle cells as the plasma membrane does in other

action potentials
.

A special feature of the sarcolemma is that it

terminal cisternal enlargements of the sarcoplasmic reticulum (termed endoplasmic reticulum
in nonmuscle cells). A transverse tubule surrounded by two SR cisternae are known as a triad, and the contact between these structures is located at the junction of the A and I bands.


References

  1. ^ Sarcolemma at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
  2. ^ Ripa, Rashelle; George, Tom; Sattar, Yasar (2022). "Physiology, Cardiac Muscle". StatPearls. StatPearls Publishing. Retrieved 4 September 2022.
  3. PMID 2099832
    .
  4. ^ Boron, Walter F. (2009). Medical Physiology 2nd edition. Philadelphia: Saunders. pp. 9–21.