Sequence Read Archive
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The Sequence Read Archive (SRA, previously known as the Short Read Archive) is a
base pairs in length.[1] The archive is part of the International Nucleotide Sequence Database Collaboration (INSDC), and run as a collaboration between the NCBI, the European Bioinformatics Institute (EBI), and the DNA Data Bank of Japan
(DDBJ).
The archive was established by the
ChIP-Seq studies as well as large-scale studies including the Human Microbiome Project and the 1000 Genomes Project.[1][2] Originally called the Short Read Archive, the name was changed in anticipation of future sequencing technologies being able to produce longer sequence reads.[3]
The volume of data deposited in the Sequence Read Archive has grown rapidly. As of September 2010, 65% of the SRA was
metagenome sequence reads.[6] Much of this data was deposited through the 1000 Genomes Project. In June 2011, the data contained within the SRA passed 100 Terabases of DNA in volume.[2]
The preferred
NCBI announced their plan to close the NCBI SRA in February 2011 due to funding reduction.[2][7] However, EBI and DDBJ announced that they would continue to support the SRA.[8] In October 2011, NCBI announced continuation of funding for the SRA.[2]
Deposition of data in the SRA is mandated by most funding agencies and
Nature Publishing Group journals require that DNA and RNA sequencing data is made available through the SRA.[9]
See also
References
- ^ PMID 18045790.
- ^ PMID 22144685.
- ^ Ostell, Jim (2009). "NCBI's Sequence Read Archive: A Core Enabling Infrastructure". Bio IT World. Retrieved 2013-01-08.
- ^ "NCBI SRA Overview". NCBI. 1 Jan 2013. Retrieved 2013-01-08.
- ^ PMID 22009675.
- ^ PMID 21062823.
- PMID 21418618.
- ^ "DDBJ will continue Sequence Raw Data Archiving". www.ddbj.nig.ac.jp. Retrieved 2 September 2014.
- ^ "Availability of data and materials : authors and referees @ npg". www.nature.com. Retrieved 2 September 2014.
External links
- European Nucleotide Archive, page for searches in SRA
- SRA homepage at NCBI.
- ERA submissions at EBI.
- DRA homepage at DDBJ.