Sequence Read Archive

Source: Wikipedia, the free encyclopedia.
Sequence Read Archive
Research center
National Center for Biotechnology Information
European Bioinformatics Institute
DNA Data Bank of Japan
Access
Websitewww.ncbi.nlm.nih.gov/sra/
www.ebi.ac.uk/ena/
trace.ddbj.nig.ac.jp/dra/index_e.html

The Sequence Read Archive (SRA, previously known as the Short Read Archive) is a

base pairs in length.[1] The archive is part of the International Nucleotide Sequence Database Collaboration (INSDC), and run as a collaboration between the NCBI, the European Bioinformatics Institute (EBI), and the DNA Data Bank of Japan
(DDBJ).

The archive was established by the

ChIP-Seq studies as well as large-scale studies including the Human Microbiome Project and the 1000 Genomes Project.[1][2] Originally called the Short Read Archive, the name was changed in anticipation of future sequencing technologies being able to produce longer sequence reads.[3]

Illumina's Genome Analyzer.[5]

The volume of data deposited in the Sequence Read Archive has grown rapidly. As of September 2010, 65% of the SRA was

metagenome sequence reads.[6] Much of this data was deposited through the 1000 Genomes Project. In June 2011, the data contained within the SRA passed 100 Terabases of DNA in volume.[2]

The preferred

API access and conversion to other formats such as FASTQ.[5]

NCBI announced their plan to close the NCBI SRA in February 2011 due to funding reduction.[2][7] However, EBI and DDBJ announced that they would continue to support the SRA.[8] In October 2011, NCBI announced continuation of funding for the SRA.[2]

Deposition of data in the SRA is mandated by most funding agencies and

Nature Publishing Group journals require that DNA and RNA sequencing data is made available through the SRA.[9]

See also

References

  1. ^
    PMID 18045790
    .
  2. ^ .
  3. ^ Ostell, Jim (2009). "NCBI's Sequence Read Archive: A Core Enabling Infrastructure". Bio IT World. Retrieved 2013-01-08.
  4. ^ "NCBI SRA Overview". NCBI. 1 Jan 2013. Retrieved 2013-01-08.
  5. ^
    PMID 22009675
    .
  6. ^ .
  7. .
  8. ^ "DDBJ will continue Sequence Raw Data Archiving". www.ddbj.nig.ac.jp. Retrieved 2 September 2014.
  9. ^ "Availability of data and materials : authors and referees @ npg". www.nature.com. Retrieved 2 September 2014.

External links