Pemphigus erythematosus
| Pemphigus erythematosus | |
|---|---|
| Other names | Senear–Usher syndrome[1] |
| Specialty | Dermatology  |
Pemphigus erythematosus is simply a localized form of pemphigus foliaceus with features of lupus erythematosus.[1][2]
Signs and symptoms
Pemphigus erythematosus patients typically present with superficially eroded lesions, or vesiculobullae, that may ooze and crust. This is especially common in areas of the body that are exposed to the sun, like the back, upper chest, and face.[3]
The symptoms of pemphigus erythematosus usually appear slowly and progress slowly. The patient might not even be aware that their pemphigus erythematosus is photosensitive, even though the distribution of the lesions should indicate that they were induced by sunlight.[3]
Causes
Pemphigus patients experience an autoimmune reaction that targets desmosomes.[4] pemphigus erythematosus relapse has been linked to atorvastatin use.[5] There has been one report of a new case of pemphigus erythematosus following topical ingenol mebutate treatment.[6]
Diagnosis
Skin biopsies are used to diagnose pemphigus erythematosus. Immunofluorescence studies are performed on perilesional skin.[3]
Treatment
It has been demonstrated that immunoadsorption and plasmapheresis are useful treatments for pemphigus erythematosus.[7][8]
See also
- Pemphigus
- List of cutaneous conditions
- List of conditions caused by problems with junctional proteins
References
- ^ ISBN 978-1-4160-2999-1.
- ISBN 0-07-138076-0.
- ^ a b c Bharti, Rakesh (December 6, 2022). "Pemphigus Erythematosus: Practice Essentials, Etiology, Epidemiology". Medscape Reference. Retrieved February 4, 2024.
- PMID 22801864.
- PMID 25258514.
- PMID 35068520.
- S2CID 22757265.
- S2CID 23582853.
Further reading
- Desai, Anand; Harris, Jessica; Motaparthi, Kiran (2018). "Enzyme-linked immunosorbent assay as a helpful diagnostic tool for pemphigus erythematosus with equivocal histologic and immunofluorescent findings". Dermatology Online Journal. 24 (8). PMID 30677852.
- Amerian, Mary L.; Ahmed, A. Razzaque (1984). "Pemphigus erythematosus". Journal of the American Academy of Dermatology. 10 (2). Elsevier BV: 215–222. ISSN 0190-9622.