Sodium aurothiosulfate
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Routes of administration | Intramuscular injection |
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Chemical and physical data | |
Formula | AuNa3O6S4 |
Molar mass | 490.17 g·mol−1 |
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Sodium aurothiosulfate, or sanocrysin, is the inorganic compound with the formula Na3[Au(S2O3)2]·2H2O. It is the trisodium salt of the coordination complex of gold(I), [Au(S2O3)2]3−. The dihydrate, which is colorless, crystallizes with two waters of crystallization. The compound has some medicinal properties as well as potential for hydrometallurgy.
Structure
The anionic complex features a linear AuS2 core and is overall
History
The salt is typically prepared by reduction of gold(III) chloride with thiosulfate:[3]
- 4 Na2S2O3 + AuCl3 → Na3[Au(S2O3)2] + Na2S4O6 + 3 NaCl
The compound was first synthesized in 1845 by Mathurin-Joseph Fordos and A. Gélis who were researching chemicals used in the Daguerrotype photographic process. It then came to be called Fordos and Gélis salt.[4][5] It went out of interest until 1924 when it was noted as a chemotherapeutic agent for tuberculosis by Holger Møllgaard in Copenhagen.[6] Other methods of synthesis were then identified.[7]
Potential applications
Like several other gold compounds, this species is used as an
Aurothiosulfate complexes have also been discussed in the context of the extraction of gold from its ores. The general approach would employ sodium or ammonium thiosulfate in place of cyanide salts as lixiviants.[10][11]
References
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- ^ Fordos MJ, Gélis A (1843). "Recherches sur la liqueur d'or employée en photographie". C.-R. Acad. Sc. (Paris). 17: 629–630.
- ^ Fordos MJ, Gélis A (1845). "Action du perchlorure d'or sur l'hyposulfite de soude". Ann. Chim. Phys. 3. 13: 394–404.
- ISSN 0028-0836.
- S2CID 101829332.
- PMID 11749494.
- ISBN 978-0801878138.
- .
- ISBN 978-3527306732.