Spermatid

Source: Wikipedia, the free encyclopedia.
Spermatid
testis of a rat. × 250.
Identifiers
MeSHD013087
FMA72294
Anatomical terminology]

The spermatid is the

haploid male gametid that results from division of secondary spermatocytes. As a result of meiosis
, each spermatid contains only half of the genetic material present in the original primary spermatocyte.

Spermatids are connected by cytoplasmic material and have superfluous cytoplasmic material around their nuclei.

When formed, early round spermatids must undergo further maturational events to develop into

spermatozoa, a process termed spermiogenesis
(also termed spermeteliosis).

The spermatids begin to grow a living thread, develop a thickened mid-piece where the

protamines during spermatid elongation. The resultant tightly packed chromatin
is transcriptionally inactive.

In 2016 scientists at

stem cells. They injected these spermatids into mouse eggs and produced pups.[1]

DNA repair

As postmeiotic germ cells develop to mature sperm they progressively lose the ability to repair DNA damage that may then accumulate and be transmitted to the zygote and ultimately the embryo.[2] In particular, the repair of DNA double-strand breaks by the non-homologous end joining pathway, although present in round spermatids, appears to be lost as they develop into elongated spermatids.[3]

Additional images

  • Scheme showing analogies in the process of maturation of the ovum and the development of the Genyo spermatids (young spermatozoa)
    Scheme showing analogies in the process of maturation of the
    spermatozoa
    )

See also

List of distinct cell types in the adult human body

References

External links