Stuart B. Levy

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Stuart B. Levy
Born
Stuart Blank Levy

(1938-11-21)November 21, 1938
Wilmington, Delaware, U.S.
DiedSeptember 4, 2019(2019-09-04) (aged 80)
Boston, Massachusetts, U.S.
Alma materWilliams College
University of Pennsylvania
OccupationMicrobiologist
EmployerTufts University School of Medicine
Spouse
Cecile Pastel
​
(m. 1983)​
Children3

Stuart Blank Levy (November 21, 1938 – September 4, 2019) was a researcher and physician at

antibiotic resistance and founded the Alliance for the Prudent Use of Antibiotics.[1]

Biography

Stuart B. Levy, M.D., Professor of Molecular Biology and Microbiology and of Medicine, was the Director of the Center for Adaptation Genetics and Drug Resistance at Tufts University School of Medicine and staff physician at the Tufts Medical Center.[2] He also served as President of the International Alliance for the Prudent Use of Antibiotics, and along with Walter Gilbert, co-founded Paratek Pharmaceuticals.[2] He was a past President of the American Society for Microbiology. Professor Levy died on September 4, 2019, and in 2020, the Tufts Center for Integrated Management of Antimicrobial Resistance was renamed in his honor.[3]

Dr. Levy led the discovery of the first energy-dependent antibiotic

efflux mechanism and efflux protein (for tetracyclines).[2] His research into multiple drug resistance revealed a regulatory locus, mar, for intrinsic antibiotic resistance and virulence among the Enterobacteriaceae and other bacteria.[2] He led the first, and perhaps only, prospective farm study showing that feed containing low dose antibiotics led to the emergence of antibiotic resistance in animals and the farm family.[2] He has published over 300 papers, edited four books and two special journal editions devoted to antibiotic use and resistance.[2] His 1992 book, The Antibiotic Paradox: How Miracle Drugs Are Destroying the Miracle, now in its second edition, has been translated into four languages.[2]

Dr. Levy received his bachelor's degree from

Institute of Medicine, the U.S. FDA and U.S. EPA.[2] In 1995 he received the Hoechst Roussel Award for esteemed research in antimicrobial chemotherapy from the American Society for Microbiology and has been awarded honorary degrees from Wesleyan and Des Moines Universities.[2] Dr. Levy received the 2011 Hamao Umezawa Memorial Award by the International Society of Chemotherapy and the 2012 Abbott-ASM Lifetime Achievement Award.[5]

Views

Levy has summarized his message by saying that he wants "prudent use of antibiotics".[6]

The book Frontiers in antimicrobial resistance : a tribute to Stuart B. Levy is based on the work of Levy.[7]

Bibliography

References

  1. ^ Smith, Harrison (September 19, 2019). "Stuart Levy, microbiologist who sounded alarm on antibiotic resistance, dies at 80". The Washington Post.
  2. ^ a b c d e f g h i j k l National Science Advisory Board for Biosecurity; National Institutes of Health; Chinese Academy of Sciences (1 November 2013), "Stuart B. Levy, M.D.", Strengthening the Culture of Responsibility with Respect to Dual Use Research and Biosecurity, Bethesda, Maryland: National Institutes of Health, archived from the original (PDF) on 9 August 2011, retrieved 27 October 2013
  3. ^ "Stuart B. Levy, MD - A Trailblazing Force Against AMR".
  4. ^ "The American Society for Microbiology honors Stuart B. Levy".
  5. ^ "Paratek Founders". paratekpharma.com. Archived from the original on 2016-04-10.
  6. ISSN 0743-1791
    . Retrieved 27 October 2013.
  7. ISBN 978-1-55581-329-1
    .


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