Nucleus (neuroanatomy)

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Subcortical gray matter
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In

gray matter, often bordered by white matter. The vertebrate
brain contains hundreds of distinguishable nuclei, varying widely in shape and size. A nucleus may itself have a complex internal structure, with multiple types of neurons arranged in clumps (subnuclei) or layers.

The term "nucleus" is in some cases used rather loosely, to mean simply an identifiably distinct group of neurons, even if they are spread over an extended area. The reticular nucleus of the thalamus, for example, is a thin layer of inhibitory neurons that surrounds the thalamus.

Some of the major anatomical components of the brain are organized as clusters of interconnected nuclei. Notable among these are the thalamus and hypothalamus, each of which contains several dozen distinguishable substructures. The medulla and pons also contain numerous small nuclei with a wide variety of sensory, motor, and regulatory functions.

In the peripheral nervous system (PNS), a cluster of cell bodies of neurons (homologous to a CNS nucleus) is called a ganglion. The fascicles of nerve fibers in the PNS (homologous to CNS tracts) are called nerves.

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