Suppository
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A suppository is a
Suppositories are ideal for infants, elderly individuals and post-operative patients, who are unable to swallow oral medications, and for individuals experiencing severe nausea and/or vomiting.[1][2][3]
Composition
Several different ingredients can be used to form the base of a suppository: cocoa butter or a similar substitute, polyethylene glycol, hydrogels, and glycerinated gelatin. The type of material used depends on the type of suppository, the type of drug, and the conditions in which the suppository will be stored.[4]
Rectal suppositories
In 1991, a study on suppository insertion in The Lancet found that the "torpedo" shape helps the device to travel internally, increasing its efficacy.[5] The findings of this single study have been challenged as there is insufficient evidence on which to base clinical practice.[6] Rectal suppositories are intended for localized or systemic action to relieve pain, constipation, irritation, inflammation, nausea and vomiting, fever, migraines, allergies, and sedation.[7][8]
Urethral suppositories
See also
Notes
- PMID 24871671.
- ^ "Dulcolax 5 mg Suppositories - Summary of Product Characteristics (SmPC) - (emc)". www.medicines.org.uk. Retrieved 2021-12-11.
- ^ Lowry, Michael (2016-02-22). "Rectal drug administration in adults: how, when, why". Nursing Times. Vol. 112, no. 8, 12–14. Retrieved 2022-04-10.
- ISBN 9780781746731.
- S2CID 23190075.
- PMID 17181671. Archived from the original(PDF) on 2020-02-29.
- PMID 31680970.
- ^ "ANTIBIOTIC/ANESTHETIC/STEROID - RECTAL SUPPOSITORIES side effects, medical uses, and drug interactions". MedicineNet. Retrieved 2021-12-11.
- ^ "Muse Suppository - Facts and Comparisons". Drugs.com. Retrieved 4 January 2013.
References
- Doyle, D., "Per Rectum: A History of Enemata", Journal of the Royal College of Physicians of Edinburgh, Vol.35, No.4, (December 2005), pp. 367–370.
- Payer, L., "Borderline Cases: How Medical Practice Reflects National Culture", The Sciences, Vol.30, No.4, (July–August 1990), pp. 38–42.