Suprofen

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Suprofen
Clinical data
AHFS/Drugs.comMicromedex Detailed Consumer Information
Routes of
administration		Oral, eye drops
ATC code
Legal status
Legal status
  • Discontinued
Pharmacokinetic data
Protein binding20%
Identifiers
  • (RS)-2-[4-(2-thienylcarbonyl)phenyl]propanoic acid
JSmol)
  • O=C(c1ccc(cc1)C(C(=O)O)C)c2sccc2
  • InChI=1S/C14H12O3S/c1-9(14(16)17)10-4-6-11(7-5-10)13(15)12-3-2-8-18-12/h2-9H,1H3,(H,16,17) ☒N
  • Key:MDKGKXOCJGEUJW-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Suprofen is a

Janssen Pharmaceutica[1] that was marketed as 1% eye drops under the trade name
Profenal.

Uses

Suprofen was originally used as

topical ophthalmic solution, typically to prevent miosis during and after ophthalmic surgery.[3] This application has been discontinued as well, at least in the US.[4]

References

  1. ^ DE 2353357, Janssen PA, Van Daele GH, Boey JM, "Antiphlogistic aroyl-substituted phenylacetic acid derivatives", issued 1974 
  2. PMID 3142236. {{cite book}}: |journal= ignored (help)CS1 maint: DOI inactive as of February 2024 (link
    )
  3. ^ "Pharmacy Compounding". Guidance for FDA Staff and Industry Compliance Policy Guides Manual. U.S. Food and Drug Administration. Archived from the original on 1 January 2009.
  4. ^ "Suprofen ophthalmic". Drugs.com. Archived from the original on 2021-09-09. Retrieved 2018-01-23.
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