TL-1238

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TL-1238
Names
Preferred IUPAC name
3-[(Dimethylcarbamoyl)oxy]-N,N-diethyl-N-methylanilinium iodide
Other names
Substance 3393
Identifiers
3D model (
JSmol
)
ChemSpider
UNII
  • InChI=1S/C14H23N2O2.HI/c1-6-16(5,7-2)12-9-8-10-13(11-12)18-14(17)15(3)4;/h8-11H,6-7H2,1-5H3;1H/q+1;/p-1
    Key: HBVVWBFVSLUJNP-UHFFFAOYSA-M
  • CC[N+](C)(CC)c1cccc(c1)OC(=O)N(C)C.[I-]
Properties
C14H23IN2O2
Molar mass 378.254 g·mol−1
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
 Extremely toxic
Lethal dose or concentration (LD, LC):
175 μg/kg (subcutaneous, mice)[1]
89 μg/kg (intravenous, mice)[1]
60 μg/kg (intravenous, mice)[2]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

TL-1238 (Substance 3393) is an extremely potent carbamate acetylcholinesterase inhibitor. It has been shown to be more potent than neostigmine.[2][3]

See also

References

  1. ^ a b Chemical Warfare Agents, and Related Chemical Problems. Parts I-II.
  2. ^
    PMID 19108106
    .
  3. PMID 18113150
    .
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