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Human protein-coding gene
TLX2 Available structures Gene ontology
Molecular function Cellular component Biological process Sources:Amigo / QuickGO
Wikidata
T-cell leukemia homeobox protein 2 is a protein that in humans is encoded by the TLX2 gene .[5] [6]
Interactions
TLX2 has been shown to
References
Further reading
Kaifi JT, Wagner M, Schurr PG, Wachowiak R, Reichelt U, Yekebas EF, Mann O, Vashist Y, Kleinhans H, Link BC, Strate T, Kalinin V, Izbicki JR (October 2006). "Allelic loss of Hox11L1 gene locus predicts outcome of gastrointestinal stromal tumors" . Oncology Reports . 16 (4): 915–9. .
Borghini S, Bachetti T, Fava M, Di Duca M, Cargnin F, Fornasari D, Ravazzolo R, Ceccherini I (April 2006). "The TLX2 homeobox gene is a transcriptional target of PHOX2B in neural-crest-derived cells" . The Biochemical Journal . 395 (2): 355–61. .
Parisi MA, Lipman NS, Clarke CM, Taylor B, Kapur RP (November 2005). "Evaluation of Hox11L1 in the fmc/fmc rat model of chronic intestinal pseudo-obstruction". Journal of Pediatric Surgery . 40 (11): 1760–5. .
Iitsuka Y, Shimizu H, Kang MM, Sasagawa K, Sekiya S, Tokuhisa T, Hatano M (August 1999). "An enhancer element for expression of the Ncx (Enx, Hox11L1) gene in neural crest-derived cells" . The Journal of Biological Chemistry . 274 (34): 24401–7. .
Tang SJ, Suen TC, McInnes RR, Buchwald M (September 1998). "Association of the TLX-2 homeodomain and 14-3-3eta signaling proteins" . The Journal of Biological Chemistry . 273 (39): 25356–63. .
(1) Basic domains
(1.1) Basic leucine zipper (bZIP )(1.2) Basic helix-loop-helix (bHLH
)
Group A Group B Group C bHLH-PAS Group D Group E Group F bHLH-COE
(1.3) bHLH-ZIP (1.4) NF-1 (1.5) RF-X (1.6) Basic helix-span-helix (bHSH)
(2) Zinc finger DNA-binding domains
(2.1) Nuclear receptor (Cys4 )
subfamily 1 subfamily 2 subfamily 3 subfamily 4 subfamily 5 subfamily 6 subfamily 0
(2.2) Other Cys4 (2.3) Cys2 His2 (2.4) Cys6 (2.5) Alternating composition (2.6) WRKY
(4) β-Scaffold factors with minor groove contacts
(0) Other transcription factors