Taenia crassiceps
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Taenia crassiceps | |
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Taenia crassiceps larvae | |
Scientific classification | |
Domain: | Eukaryota |
Kingdom: | Animalia |
Phylum: | Platyhelminthes |
Class: | Cestoda |
Order: | Cyclophyllidea |
Family: | Taeniidae |
Genus: | Taenia |
Species: | T. crassiceps
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Binomial name | |
Taenia crassiceps (Zeder, 1800)
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Taenia crassiceps is a tapeworm in the family Taeniidae. It is a parasitic organism whose adult form infects the intestine of carnivores, like canids. It is related to Taenia solium, the pork tapeworm, and to Taenia saginata, the beef tapeworm. It is commonly found in the Northern Hemisphere, especially throughout Canada and the northern United States.
Natural intermediate hosts of this organism are usually small rodents and moles. The larval stages of T. crassiceps develop subcutaneously or in their body cavities as cysticerci which are cyst-like structures.[1]
Taenia crassiceps begins its life in the intestines of wild canines, such as the wolf. Inside the wolf, the tapeworm reproduces. Its eggs are passed in the wolf's feces and are eaten by a rat. When the rat is eaten by another wolf, the parasite's life cycle repeats. Taenia crassiceps rarely infect humans, but if they do, they often cause ocular larva migrans that can progress to blindness. An adult human's immune system typically removes the parasite before permanent damage is done, however, juveniles are typically less defended.
Human pathologies
Taenia crassiceps is described as an opportunistic infection in severe immunodeficiency, as in AIDS.[2] But human infection are rare, with only eight cases reported and individuals who were infected tended to be immunosuppressed patients where parasites accumulated on skeletal muscles and subcutaneous tissue, and some with intraocular infections.[3] Rodents are natural intermediate hosts, and they harbor the cyst-like larvae (metacestodes, cysticerci) in the peritoneal cavity, where they multiply by asexual budding. Humans serve as intermediate hosts when food or water contaminated with feces from infected
A case of intracranial T. crassiceps tapeworm cysticercosis with severe involvement of the cerebellum is described. A 51-year-old German woman was hospitalized because of progressive
Symptoms
There may be no symptoms. Symptoms may include: Headaches, Nausea, and Vomiting[6]
Laboratory studies
Positive test results from a serum enzyme-linked immunosorbent assay ELISA for anticysticercal antibodies help confirm the diagnosis; however, negative test results do not exclude cysticercosis. A CBC count may reveal eosinophilia.[7]
Treatments
Surgical removal is mandatory for individuals with intraoscular cysts. Oscular cysticercosis can be effectively treated with Anthelminthics such as
Immunoregulation
The immune response elicited by T. crassiceps and its antigens in human and mice cells were studied, suggesting that it had a strong capacity to induce chronic Th2-type responses that are primarily characterized by high levels of Th2 cytokines, low proliferative response in lymphocytic cells, immature and LPS-tolerogenic profile in dendritic cells, the recruitment of myeloid-derived suppressor cells, and activated macrophages.[9]
References
Includes public domain text from the CDC as cited
- S2CID 205049949.
- PMID 9537478.
- S2CID 205049949.
- PMID 16837716.
- ^ Ocular Cysticercosis~workup at eMedicine
- ^ Ocular Cysticercosis~treatment at eMedicine
- PMID 23484125.)
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